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The plane was coming from Louisville, Ky. towards Birmingham-Shuttlesworth International Airport when it crashed. 

The National Transportation Safety Board, whose members are investigating the cause of the crash, are hoping to recover the plane’s data-recording “black boxes.” 

The pilot and co-pilot were the only people aboard the plane, said company spokesman Jeff Wafford. 

The crash took place at about 5 am local time. The plane reportedly struck a massive tree, clipping some power lines. 

"This incident is very unfortunate, and our thoughts and prayers are with those involved," UPS Airlines President Mitch Nichols said in a statement. "We place the utmost value on the safety of our employees, our customers and the public. We will immediately engage with the National Transportation Safety Board's investigation, and we will work exhaustively on response efforts."

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